2005 Sessions Downloads

CoSMoS 2005 Presentations

August 8-11, 2005
Bristol, Rhode Island

Download presentations (PDF files except as noted)

Challenges in Chirality
Chiral Separation of Basic Compounds in HPLC Using Acidic Additives
— Dr. Roger Stringham, Chiral Technologies

New Classes of Chiral Selectors for LC, CE, and GC
— Dr. Daniel Armstrong, Iowa State University, Sponsored by Waters Corporation

Optimizing Throughput and Minimizing Cost in Semi-Prep SFC
— Dr. Terry Berger, AccelaPure Corp

Automated Methods Development
Integrated approach to HPLC method development: Using all the tools in the chromatographer’s toolbox
— Dr. Rosario LoBrutto, Novartis Pharmaceuticals

Approaches for HPLC Method Development and Optimization for Late Stage Pharmaceuticals
— Dr. Ken Norris, Pfizer

Strategies for the Systematic Development of Reversed-Phase HPLC Separations
— Dr. Tom Jupille, LC Resources

Alternatives to Traditional LC/MS
Desorption Electro-spray Ionization (DESI) Mass Spectrometry: Small Organics, Peptides and Proteins on Insulators and in Biological Tissues
— Justin Wiseman, Purdue University-Sponsored by Thermo Electron

Characterization and Performance of MALDI on a Triple Quadrupole Mass Spectrometer for Analysis & Quantification of Small Molecules (a powerpoint file)
— Dr. Jason Gobey, Pfizer Global Research

Development Imaging Mass Spectrometry for Direct Tissue Analysis of Pharmaceuticals
— Dr.Yunsheng (Tony) Hsieh, Schering-Plough

Practices in Information Extraction and Data Management
Identification/Dereplication of Natural Products by LC-UV-MS
— Dr. Deborah Zink, Merck

State of the Industry: Electronic Laboratory Notebook Technology
— Michael Elliott, Atrium Research

Extracting Accurate Mass Information for Compound Identification from Complex Sample Matrices
— Doug McIntyre, Agilent Technologies

Problem Solving in Metabolism
Providing NMR Solutions in Drug Metabolism – To Hyphenate or Not to Hyphenate: Is that the Question?
— Dr. Steve Castellino, GSK

Is LC-MS/MS Enough for Characterization of Novel and Regioisomeric Metabolites for Drug Candidates?
— Dr. Chandra Prakash, Pfizer

Unknown Identification vs. Molecular Weight Confirmation – How Much Mass Accuracy is Enough?
— Dr. Daniel Norwood, Boehringer Ingelheim

Recent Work in Analytical Chemistry
Application of HPLC-NMR, HPLC-MS and MS/MS to Investigate the Environmental Fate of Fluoroquinolone Antibiotics
— Dr. Cindy Larive, University of California Riverside, Sponsored by the CoSMoS Conference

Analysis of Pharmaceutical Formulations using Ion
Mobility/Time-of-Flight Mass Spectrometry combined with Desorption Electrospray Ionization

— Dr. Daniel Weston, Nottingham Trent University, UK- Sponsored by P & G Pharmaceuticals, Inc.

Direct Analysis Under Ambient Conditions without Sample Preparation: “Instant Gratification” for Small Molecule Analysis
— Dr. Robert B. Cody, JEOL, USA