2007 Sessions Downloads

CoSMoS 2007 Presentations

July 30- August 1, 2007
Chapel Hill, NC

Downloads (PDF File unless noted)

Session 1 – Applied Science of Chromatography
Session Chair: Dr. Nelu Grinberg, Boehringer-Ingelheim Pharmaceuticals, Inc.

A New Approach to Retaining Hydrophilic Compounds in HPLC
— Professor Joe Pesek, San Jose State University

Ultra-High Pressure Liquid Chromatography
— Professor James Jorgenson, University of North Carolina

Mechanistic Aspects of Chiral Discrimination on Polysacharides Phases
— Nelu Grinberg, Boehringer, Ingelheim Pharmaceutical, Inc.

Session 2 – Analyzing Complex Mixtures
Session Chair: Dr. David Stranz, Sierra Analytics, Dr. Ioana Popa-Burke, GlaxoSmithKline

FT-ICR MS Sheds Light on Nature’s Complexity
— Ryan P. Rodgers, Florida State University

Analysis of Perfluorinated Compounds in Complex Environmental and
Biological Matrices

— Mark Strynar, EPA

Comprehensive Metabolomic Profiling for Understanding the Mechanisms of Diabetes and Obesity
— Michael Muehlbauer, Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center

Session 3 – Making Unknowns Known
Session Chair: Melissa Gomez, GlaxoSmithKline

Finding and Identifying Metabolites: Why Resolution and Accurate Mass Matters
— Kevin Bateman, Merck Frost

Library Searching without Libraries
— Dan Sweeney, MathSpec

Structure Elucidation and Metabolomics (Presentation not available)
— Eric Milgram, Metabolon, Inc.

Session 4 – New Directions in Pharmaceutical Profiling
Session Chair: Dr. Oliver McConnell, Wyeth Research

Impact of ADME/TOX in Drug Discovery: Past, Present and Future
— Li Di, Wyeth Research

Future Trends in Drug Discovery: The New Drug Metabolism Scientists
— Dr. Theresa Wilson, Pfizer

Non-Conventional Approach to Solubility Measurement without Filtration by an In Situ UV Fiber Optic Method and the Effects of Excipients on Solubility of Sparingly Soluble Compounds
— Konstantine Tsinman , pION Inc.

Session 5 -Novel Technologies: “Alternatives In The Face of Chemical Diversity”
Session Chair: Michael Balogh, Waters Corporation

Lead Optimization in a Nano-Droplet: Leveraging Orthogonal Technologies to Improve Throughput for Drug Discovery
— Paul Schnier, Amgen

Investigation of the Potential of IMS and FAIMS for the Measurement of Trace Level Impurities in Formulated Drug Products
— Alice Laures, GlaxoSmithKline

Overcoming Signal Suppression and Other Matrix Effects in LC-MS Using Electron Ionization
— Professor Achille Cappiello, University of Urbino

Excellence In Science Award Winner
Douglas Kiehl, Eli Lilly & Company