2012 Sessions Downloads

CoSMoS 2012 Presentations

September 10 – September 12, 2012
Providence, RI

Downloads (PDF Files unless otherwise noted)

Session 1 

Increased Efficiency (U (H)PLC) is great- but whatever happened to chromatographic “Selectivity”

Chair: Wolfgang Goetzinger

Molecularly Imprinted Polymers (MIPs) as Customizable Stationary Phases
— Ken Shimizu, University of South Carolina

Modifying Chromatographic Selectivity Through Solvent and Phase Changes
— Bill Farrell, Pfizer, La Jolla, CA

Combining Multi-linear Gradient Profile and Stationary Phase Optimised Selectivity Predictions for Enhanced LC Method Development
— Frederic Lynen, Ghent University, Belgium

Session 2

Method Development Olympics
Chair: Kenneth Fountain, Waters Corporation
Samples and Overall Results

Gold medal (as awarded by attendee ballot)
— Farrand, Pfizer, Groton, CT

Silver medal (as awarded by attendee ballot)
— Lynen, Ghent University, Belgium

Bronze medal (as awarded by attendee ballot)
— Debrus, University of Geneva, Switzerland

Session 3
Innovation in Sample Preparation Technology Session
Chair: William Farrell

Flexibility of the QuEChERS Approach for Different Sample Preparation Applications
— Steven J. Lehotay, USDA

Why am I Still Doing Sample Preparation the Hard Way? What if….
— Claude Mallet, Waters CorporationLaboratory

Case Studies in Sampling, Preparation, and Analysis in Mechanistic Biology
— Mark Hayward, Lundbeck Pharma

Session 4
Sample Preparation: Method Strategies & Automation Workshop
Workshop Chairs: Beverly Nickerson and Gwen Kuehl

Sample Preparation Method Development Workflow for Solid Oral Dosage Forms
— Beverly Nickerson, Pfizer, Groton, CT

Automation in Sample Preparation
— Gwen Kuehl, Merck, NJ

Session 5
Ion Mobility
Chair: Justin Stroh

Using Ion Mobility to Widen the Structure Identification Bottleneck in Non-Targeted Metabolomics
— David Grant, University of Connecticut

Ion Mobility Lipidomics
— Giuseppe Astarita, Waters Corporation

Session 5 Parallel
Photostability Workshop
Chair: Allen Zielnik, Atlas Material Testing Technology LLC

Overview of Photostability / Fundamentals
— Allen Zielnik, Atlas Material Testing Technology LLC

Session 6
Nanotechnology and Microfluidics: Plenty of Room at the Bottom
Chairs: David Stranz and Douglas Kiehl

Digital Microfluidics for Sample Processing and Analysis of Small Molecules
— Aaron Wheeler, University of Toronto

Think Big Then Shrink: Micro & Nano Tools for Biomedical Applications (Presentation not available)
— Michelle Khine, University of California, Irvine

Session 6 Parallel

Photosafety Guidance and Current Best Practices (Presentation not available)
Chair: Karen Alsante, Pfizer

Surprising Aspects of Light: Why Photostability Matters (Presentation not available)
— Allen Zielnik, Atlas Material Testing Technology LLC

Can Light Absorption and Photostability Data be Used to Assess the Photosafety Risks in Patients for a New Drug Molecule? (Presentation not available)
— Karen Alsante, Pfizer

A Case Study for In-use Photostability of Photosensitive IV Product (Presentation not available)
— Andreas Abend, Merck

Session 7
Food Chemistry
Chairs: Jeff Standish and Elaine Ricicki

Considerations in Regulatory Applications of Mass Spectrometry in Food Safety
— Janie Dubois, University of Maryland, JIFSAN

Beer-omics: Molecular Fingerprinting of Craft Beers by High Resolution Mass Spectrometry
— Christine Hughey, James Madison University

Targeted Unknown LC(ESI+) -Q/TOFMS Analysis of Quercetin Metabolites in Plasma
— Allyson Mitchell, UC Davis

Session 7 Parallel
New Developments in Drug
Chair: Steve Baertschi, Eli Lilly & Company

Challenges in Low-level Drug Product Degradant Structure ID: A Focus on Sample Source (Presentation not available)
— Todd Zelesky, Pfizer

High Resolution Mass Spectrometry for Impurity Structural Elucidation: the Latest Hardware and Software Tools (Presentation not available)
— Charles Cheng, Pfizer

Thermal Oxidative Deg Pathways of a PPAR Gamma (Presentation not available)
— Biren Joshi, GlaxoSmithKline

Session 8
Emerging Solutions
for Sampling and Analysis in Complex Problem Domains
Chairs: David Stranz and Douglas Kiehl

Bio Electronics: From Novel Concept to Practical Applications
— Evgeny Katz, Clarkson University

Structural Elucidation of Unknowns in Biodiesel Using Accurate Mass GC/MS and LC/MS (Presentation not available)
— Douglas Stevens, Waters Corporation

Session 8 Parallel
Developments in Degradation Part 2

Degradation in Nanocrystals of Liposomal Formulations (Presentation not available)
— Robert Reed, Celsion Corporation

New Ways to Visualize the Results of Forced Degradation Studies (Presentation not available)
— Steven Baertschi, Eli Lilly & Company

Novel CP-690, 550 Drug-Excipient Degradation Chemistry in a Topical Formulation Containing Poly Ethylene Glycol (Presentation not availalble)
— Chris Foti, Pfizer