2014 Sessions Downloads

CoSMoS 2014 Presentations

August 10 – August 13, 2014
Williamsburg, VA

Downloads (PDF Files unless otherwise noted)


Session 1

Biology Meets Small Molecule Science

Chairs:Elizabeth Hamelin, CDC
Justin Stroh, Pfizer


Understanding the potential of macromolecules in analytical method development

Jonas W. Perez
Battelle Memorial Institute, Columbus, OH


Development of an Aptasensor for the Detection of Paralytic Shellfish Toxins

Jeffrey A. DeGrasse
Center for Food Safety and Applied Nutrition, US Food and Drug Administration, College Park, Maryland


Novel ADME Strategies for ADC Drug Development

Xiaogang Han
PDM NBE, Pfizer Inc.


Session 2

3rd Annual Method Development Olympics

Kevin Gauger, Catalent
William Farrell, Pfizer
Kenneth Fountain, Waters

Takeda – Amy McCusker

Averica – Jeffrey Kiplinger

Pfizer – Ruchi Mehta


 Session 3

The future of chromatography – what will separation systems look like in the next decade

Wolfgang Goetzinger, Amgen
William Farrell, Pfizer


The Future of Chromatography

Georges A. Guiochon
University of Tennessee, Knoxville and Oak Ridge National Laboratory Distinguished Scientist


Session 4

Investigations:  Making the Unknown Known  – forensics and analytical design-of-experiment challenges

Douglas Kiehl, Lilly
Justin Stroh, Pfizer


Process Patent Protection: Protecting Intellectual Property via Ambient Stable Isotopes

John P. Jasper
Nature’s Fingerprint® / MIT LLC, Niantic, CT


Analytical Testing for the Cannabis Industry: Application of Ultra Performance Convergence Chromatography

Christopher Hudalla
Proverde Laboratories, Franklin, MA


Forensic Toxicology:  Analytical Strategies For Detecting And Reporting Compounds In A Legal Environment

Lucas Zarwell
Office of the Chief Medical Examiner, Public
Safety & Justice Cluster, Washington, D.C


Session 5

Predictive Technology

Karen Alsante, Pfizer
Steven Baertschi, Lilly


Predicting Rates of Degradation as a Function of Dosage Strength

Allison Dill
Lilly, Indianapolis, IN


Water Activity Measurements: The Achilles Heel of Accelerated Stability Predictions

Brian Pack
Lilly, Indianapolis, IN


Oxidative Prediction: Azo Initiator Pharma Consortium Effort and Results

Marcela Nefliu
Merck, Sharp & Dohme, NJ


Session 6

USP Standards and Monograph Modernization

Kevin Hool, Vice President of R&D
USP, Rockville. MD


Session 7

Modern Structure Elucidation

David Stranz, Sierra Analytics
Karen Alsante, Pfizer


The mzCloud: Cloud Computing in Mass Spectrometry

Robert Mistrik
HighChem, Slovakia


Higher Order Tandem MS Applied to Natural Product Structure and Reactivity Elucidation

Kevin A. Schug
The University of Texas at Arlington, Arlington TX
Presentation sponsored by Shimadzu


Application of Structure Elucidation Techniques and Topochemical Principles to Understand Solid-State Photoreactivity

Greg Sluggett
Pfizer, Groton, CT


Session 8

Wisdom of the Crowd – The Changing Scientific Workforce

Jeff Standish, ACS
William Farrell, Pfizer
Douglas Kiehl, Lilly


Session 9

Understanding Complex Samples

Karen Alsante, Pfizer
David Stranz, Sierra Analytics
Michael Balogh, Waters


Targeted Petroleomics: Lessons Learned over the Past 15 Years

Ryan P. Rodgers
Future Fuels Institute, National High Magnetic Field Laboratory, Florida State University


Frontiers in Selective Low Level Detection of Genotoxic Impurities chemical derivatization in conjunction with mass spectrometry for quantitation of genotoxic impurities

David Liu
GlaxoSmithKline, King of Prussia, PA


The chemical nature of hydrocarbon-based biofuels from algae viewed by recent advances in separations, mass spectrometry and informatics

Patrick G. Hatcher
Batten Endowed Chair of Physical Sciences
Old Dominion University, Norfolk, VA


Session 10

Real-Time Sampling

Michael Balogh, Waters David Stranz, Sierra Analytics
Jeff Standish, ACS


Process Analytical Technology and Online Reaction Monitoring Techniques

Ruchi Mehta
Pfizer, Groton, CT


The Automated Temperature Controlled Analysis of Antibody-Drug Conjugates and Advanced Logistics & Robotic Liquid Handling Quality Concepts for use in Regulated Bioanalysis

Joseph A. Tweed
Pfizer Groton, CT


Chemical process understanding using RxnNMR

David Anthony Foley
Pfizer, CT


Session 11

New Horizons and Trends in Analytical Chemistry Techniques

Elaine Ricicki, Agilent
Christine Aurigemma, Pfizer
Douglas Kiehl, Lilly


Analysis of leachables in silicone caps using 2D LC/MS/MS

Claude R. Mallet
Waters Corporation, Milford, MA


I Feel the Need. The Need for Speed: Integrated Solid Phase Extraction/Autosampler for Support of ADME Assays in Drug Discovery

Panos Hatsis
Novartis Institute for Biomedical Research, Cambridge, MA


Recent Advances in Column Technology: Active Flow Technology

R.A. Shalliker
Australian Centre for Research on Separation Science, School of Science and Health, University of Western Sydney, Parramatta, NSW