1-(4-Aminophenyl)ethanone oxime

4-Aminoacetophenone oxime is an organic compound that is soluble in water and methanol. It has a molecular weight of 169.17 g/mol, a melting point of 190 °C, and a boiling point of 260 °C. 4-Aminoacetophenone oxime has been shown to have antimicrobial activity against Gram-positive bacteria, such as Staphylococcus aureus, but not against Gram-negative bacteria. This compound can be used as a ligand for metal ions such as copper and zinc, which are important in biological processes. The magnetic properties of 4-aminoacetophenone oxime make it possible to detect the molecule using nuclear magnetic resonance spectroscopy. 4-Aminoacetophenone oxime can be synthesized by reacting 5-nitrosalicylaldehyde with ammonium acetate in the presence of hydrochloric acid: