trans-3-Nitrocinnamic acid

Trans-3-Nitrocinnamic acid is a white solid that can be obtained by the nitration of cinnamic acid. Trans-3-Nitrocinnamic acid is an isoenzyme as it has different chemical properties than cis-3-nitrocinnamic acid. The intermolecular hydrogen bonding and vibrational frequencies are different in trans-3-nitrocinnamic acid, which causes the dipole to change and increases the solubility in water. The genotoxic activity of trans-3-nitrocinnamic acid was evaluated using the Ames test, which showed that it is not mutagenic. However, there were some genotoxic effects observed in rats after applying trans-3-nitrocinnamic acid on skin.